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KMID : 0870420170210040194
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Korean Journal of Hepato-Biliary-Pancreatic Surgery
2017 Volume.21 No. 4 p.194 ~ p.198
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Clinical usefulness of FDG-PET in patients with hepatocellular carcinoma undergoing surgical resection
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Cho Kyung-Jin
Choi Nam-Kyu
Shin Min-Ho
Chong A-Ri
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Abstract
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Backgrounds/Aims: Diagnosis and staging of hepatocellular carcinoma (HCC) is critical because of the variety of treatment methods and prognosis. [18F]fludeoxyglucose-positron emission tomography/computed tomography ([18F]FDG-PET/CT) has been suggested as a diagnostic modality in HCC. The purpose of this study is to evaluate the accuracy of FDG-PET for staging of HCC after surgical resection and histological confirmation.
Methods: We retrospectively collected data of 56 patients that underwent FDG-PET before surgical resection for HCC March 2011-May 2017, all of whom were suitable for resection by conventional HCC staging. Results of the maximal standardized uptake value (SUVmax) were compared with histological confirmation.
Results: A larger tumor size was related with higher SUVmax (≥4.9). The serum alpha-feto protein was associated with SUVmax. Recurrence rate was higher in patients with higher SUVmax and patients with lower SUVmax had a better survival rate.
Conclusions: The SUVmax correlates well with tumor size and factors associated with biological behavior of HCC such as alpha-feto protein, and it could be a beneficial modality in providing prognostic information for HCC. (Ann Hepatobiliary Pancreat Surg 2017;21:194-198)
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KEYWORD
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Hepatocellular carcinoma, [18F]fludeoxyglucose positron emission tomography, Standardized uptake value (SUV)
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